| Current Investments |
|---|
 | AccentCare Irvine, California Home care services to the elderly
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 | Archemix Cambridge, Massachusetts Discovery and development of aptamer-based therapeutics
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 | AVEO Pharmaceuticals Cambridge, Massachusetts Discovery and development of innovative cancer therapeutics
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 | BAROnova Goleta, California Novel devices for the treatment of gastrointestinal diseases
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 | Codon Devices Cambridge, Massachusetts Commercial applications of synthetic biology
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 | Fidelis SeniorCare Chicago, Illinois Comprehensive care management
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 | Generation Health Upper Saddle River, New Jersey Health management company
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 | Helicos BioSciences Cambridge, Massachusetts High-throughput DNA sequencing instruments
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 | Hyperion Therapeutics South San Francisco, California Specialty biopharmaceuticals
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 | iZumi Mountain View, California Drug discovery and regenerative medicine
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 | OpGen Gaithersburg, Maryland Microbial genome analysis
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 | Pervasis Therapeutics Cambridge, Massachusetts Treatment of cardiovascular diseases
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 | Predictive Biosciences Lexington, Massachusetts Novel biomarkers revolutionizing cancer management
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 | RedBrick Health Minneapolis, Minnesota Consumer-directed healthcare platform
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 | Yoga Works Santa Monica, California Network of alternative health fitness centers
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Previous Investments |
|---|
 | Aspect Medical Systems Newton, Massachusetts Anesthesia measurement devices (Nasdaq: ASPM)
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 | Conor Medsystems Menlo Park, California Second generation drug-eluting stents (Acquired by Johnson & Johnson)
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| Critical Care America Westboro, Massachusetts Home infusion therapies (Merged with Medical Care America, Inc.)
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 | Delos WomensHealth Dallas, Texas OB/GYN physician practice management company
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 | EXACT Sciences Maynard, Massachusetts Genomics-based technologies (Nasdaq: EXAS)
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 | GenVec Gaithersburg, Maryland Novel gene therapy products (Nasdaq: GNVC)
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 | Magen BioSciences Waltham, Massachusetts Dermatology and specialty pharmaceutical company
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 | Mariner Health Group Mystic, Connecticut Transitional care facilities (NYSE: MPN)
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 | MedicaLogic/Medscape Hillsboro, Oregon Medical healthcare website (Merged with MedicaLogic, Inc. to form MedicaLogic/Medscape, Inc.)
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 | Mitotix Cambridge, Massachusetts Drugs to treat cancer and diseases (Acquired by GPC Biotech)
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 | Nations Healthcare Atlanta, Georgia Home care services (Acquired by Home Medical of America)
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 | NuGenesis Technologies Westborough, Massachusetts Information management solutions for the laboratory (Acquired by Waters Corporation)
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 | Odyssey HealthCare Dallas, Texas Hospice care provider (Nasdaq: ODSY)
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 | Ontogeny, Inc. Cambridge, Massachusetts Developmental biology (Merged with Creative BioMolecules, Inc. and Reprogenesis, Inc. to form Curis, Inc.)
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 | Origin MedSystems Indianapolis, Indiana Innovative surgical devices (Acquired by Eli Lilly and Company)
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 | PerSeptive Biosystems Foster City, California Biopharmaceutical products (Acquired by The Perkin-Elmer Corporation)
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 | PRAECIS PHARMACEUTICALS Cambridge, Massachusetts Drug screening processes (Nasdaq: PRCS)
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 | Radiant Medical Redwood City, California Platform technology that cools body temperature
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 | Somatix Therapy Atlanta, Georgia Gene transfer technology
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 | Theraphysics Brentwood, Tennessee Managed care physical therapy (Acquired by MATRIX Rehabilitation)
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 | Total Renal Research Minneapolis, Minnesota Kidney dialysis treatment centers (Not Traded: RCGI)
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 | UroMed Norwood, Massachusetts Medical products for urological disorders (Nasdaq: URMD)
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 | US Labs Irvine, California Anatomic pathology laboratory (Acquired by LabCorp)
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